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Idebenone (pronounced eye-deb-eh-known) is an organic compound of the quinone family and promoted commercially as a synthetic analog of Coenzyme Q10 (CoQ10).
Idebenone is claimed to have properties similar to CoQ10 in its antioxidant properties.[specify]
Idebenone is different from Coenzyme Q10 in one very important way. During a hypoxic (low oxygen) condition, CoQ10 can switch function from an anti-oxidizing to an auto-oxidizing process. This auto-oxidation rapidly produces free radicals which damage the tissues of the body.[verification needed]
Idebenone is said to perform the same functions as CoQ10 without the risk of an auto-oxidation reaction.[verification needed]
Idebenone is said to promote NGF (nerve growth factor) in the brain.[verification needed] It appears to reduce tinnitus (ringing in the ears).[verification needed] Idebenone has also been used in topical applications to treat wrinkles.
Takeda Pharmaceuticals studied Idebenone which it got approved for Alzheimer's disease and Stroke.
Idebenone has reduced the rate of deterioration of cardiac function in patients with Friedreich's ataxia
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